All functions

bulk_generator()

Generate artificial bulk RNA-seq samples based on simulation

celltype_expression()

Compute cell type specific gene expression

comparedeg_scatter()

Generate a scatter plot comparing two differential expression results

comparegsea_scatter()

Generate a scatter plot comparing two gene set enrichment analysis results

compute_metrics()

Statistical evaluations of predicted cell proportions

construct_ref()

Integration of single-cell/nuclei RNA-seq data as reference

gsea_heatmap()

Heatmap to demonstrate enrichment of selected gene-sets

gsea_rwplot()

GSEA random-walk plot

gsea_sumplot()

Summary plot of gene set enrichment analysis

load_scdata()

Load, filter and normalize scRNA-seq/snRNA-seq data

prepare_rnk()

Prepare .rnk file for GSEA preranked analysis

prop_barplot()

Bar plot of cell type proportions across samples

refdata

Integrated scRNA-seq reference for breast tissue (subset)

reformat_gmt() read_gmt() write_gmt()

Methods to manipulate .gmt files

run_de()

Differential expression analysis

scaling()

Normalization of gene expression data

scdecon()

Deconvolution of bulk RNA-seq data

transformation()

Transformation of gene expression data